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Clostridium difficile MazF Toxin Exhibits Selective, Not Global, mRNA Cleavage

29 Apr 2012

Abstract excerpt

Clostridium difficile is an important, emerging nosocomial pathogen. The transition from harmless colonization to disease is typically preceded by antimicrobial therapy, which alters the balance of the intestinal flora, enabling C. difficile to proliferate in the colon. One of the most perplexing aspects of the C. difficile infectious cycle is its ability to survive antimicrobial therapy and transition from inert...

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PMID: 22544268
DOI: 10.1128/jb.00217-12

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