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Type I toxin-antitoxin systems contribute to mobile genetic elements maintenance in <i>Clostridioides difficile</i> and can be used as a counter-selectable marker for chromosomal manipulation

2020-03-05

Abstract excerpt

<h4>ABSTRACT</h4> Toxin-antitoxin (TA) systems are widespread on mobile genetic elements as well as in bacterial chromosomes. According to the nature of the antitoxin and its mode of action for toxin inhibition, TA systems are subdivided into different types. The first type I TA modules were recently identified in the human enteropathogen Clostridioides (formerly Clostridium ) difficile . In type I TA, synthes...

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Literature Corpus work
ab2cbbf3-f7e7-57a7-a966-fb52ea694224
DOI
10.1101/2020.03.04.976019
Open publication

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Type I toxin-antitoxin systems contribute to mobile genetic elements maintenance in <i>Clostridioides difficile</i> and can be used as a counter-selectable marker for chromosomal manipulationDOI 10.1101/2020.03.04.976019
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