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Article

Effect of the interleukin-1 genotype on monocyte IL-1beta expression in subjects with adult periodontitis.

Journal of periodontal research - 1 Jun 2000

Mark L L, Haffajee A D, Socransky S S, Kent R L, Guerrero D, Kornman K, Newman M, Stashenko P

Abstract excerpt

An association has been reported between polymorphisms in the genes encoding IL-1alpha (-889) and IL-1beta (+3953) (periodontitis susceptibility trait, PST), and an increased severity of periodontitis (18). The IL-1beta polymorphism was reported to correlate with increased IL-1beta expression by monocytes in response to bacterial stimulants. In the present study, we determined if PST positive subjects with...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10929872
DOI: 10.1034/j.1600-0765.2000.035003172.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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