Article
The influence of interleukin gene polymorphism on expression of interleukin-1beta and tumor necrosis factor-alpha in periodontal tissue and gingival crevicular fluid.
Journal of periodontology - 1 Jun 1999
Engebretson S P, Lamster I B, Herrera-Abreu M, Celenti R S, Timms J M, Chaudhary A G, di Giovine F S, Kornman K S
Abstract excerpt
BACKGROUND: A specific composite genotype of the polymorphic interleukin-1 (IL-1) gene cluster has recently been associated with severe periodontitis. One polymorphism of the composite periodontitis-associated genotype (PAG) has been functionally linked with expression of high levels of IL-1. The...
Topics
- Adult
- Analysis of Variance
- Dental Scaling
- Female
- Genetic Predisposition to Disease
- Gingiva
- Gingival Crevicular Fluid
- Humans
- Interleukin-1
- Male
- Middle Aged
- Periodontal Pocket
- Periodontitis
- Polymerase Chain Reaction
- Polymorphism, Genetic