Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The influence of interleukin gene polymorphism on expression of interleukin-1beta and tumor necrosis factor-alpha in periodontal tissue and gingival crevicular fluid.

Journal of periodontology - 1 Jun 1999

Engebretson S P, Lamster I B, Herrera-Abreu M, Celenti R S, Timms J M, Chaudhary A G, di Giovine F S, Kornman K S

Abstract excerpt

BACKGROUND: A specific composite genotype of the polymorphic interleukin-1 (IL-1) gene cluster has recently been associated with severe periodontitis. One polymorphism of the composite periodontitis-associated genotype (PAG) has been functionally linked with expression of high levels of IL-1. The purpose of this study was to test whether gingival crevicular fluid (GCF) levels of IL-1beta and tumor necrosis...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Analysis of Variance
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gingiva

Share to Interleukin-1

Share to Periodontitis

Share to Polymerase Chain Reaction

Share to Polymorphism, Genetic

Share to Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 10397510
DOI: 10.1902/jop.1999.70.6.567

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The influence of interleukin gene polymorphism on expression of interleukin-1beta and tumor necrosis factor-alpha in periodontal tissue and gingival crevicular fluid.PMID 10397510Read ↗

Clinical Relevance of Cytokines Gene Polymorphisms and Protein Levels in Gingival Cervical Fluid from Chronic Periodontitis Patients.Semantic proximity Read ↗

Interleukin-1 genetic association with periodontitis in clinical practice.Semantic proximity Read ↗

Polymorphisms within the IL-1 gene cluster: effects on cytokine profiles in peripheral blood and whole blood cell cultures of patients with aggressive periodontitis, juvenile idiopathic arthritis, and rheumatoid arthritis.Semantic proximity Read ↗

Cytokine gene polymorphisms associate with microbiogical agents in periodontal disease: our experience.Semantic proximity Read ↗

Association between interleukin-1 gene polymorphism and severity of chronic periodontitis in a south Indian population groupSemantic proximity Read ↗

Interleukin-1 as a genetic marker for periodontitis: review of the literature.Semantic proximity Read ↗

GCF IL-1beta profiles in periodontal disease.Semantic proximity Read ↗

Interleukin-1 composite polymorphism as a risk factor for chronic periodontitis: a review.Semantic proximity Read ↗

Association of interleukin-1 gene variations with moderate to severe chronic periodontitis in multiple ethnicities.Semantic proximity Read ↗

Association of interleukin-1 polymorphisms with aggressive periodontitis.Semantic proximity Read ↗

The interleukin-1 genotype as a severity factor in adult periodontal disease.Semantic proximity Read ↗

Analysis of the interleukin-1 and interleukin-6 polymorphisms in patients with chronic periodontitis. A pilot study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.