Article
The interleukin-1 genotype as a severity factor in adult periodontal disease.
Journal of clinical periodontology - 1 Jan 1997
Kornman K S, Crane A, Wang H Y, di Giovine F S, Newman M G, Pirk F W, Wilson T G, Higginbottom F L, Duff G W
Abstract excerpt
Although specific bacteria, dental plaque, and age are associated with periodontal disease, there are currently no reliable predictors of periodontitis severity. Studies in twins have suggested a genetic contribution to the pathogenesis of periodontitis, but previous attempts to identify genetic...
Topics
- Adult
- Chi-Square Distribution
- Genetic Markers
- Genetic Predisposition to Disease
- Genotype
- Humans
- Interleukin-1
- Logistic Models
- Odds Ratio
- Periodontitis
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Smoking
- Statistics, Nonparametric
