Article
Gene polymorphisms in pro-inflammatory cytokines are associated with systemic inflammation in patients with severe periodontal infections.
Cytokine - 7 Oct 2004
D'Aiuto F, Parkar M, Brett P M, Ready D, Tonetti M S
Abstract excerpt
The inflammatory response to chronic infections such as periodontitis may be central to the systemic implications of these diseases. This study examined the possible association between specific gene polymorphisms and the systemic inflammatory response in individuals suffering from severe generalized periodontitis. Ninety-four subjects with periodontitis were genotyped for polymorphisms in IL-1A (-889), IL-1B...
Topics
- Base Sequence
- Biomarkers
- C-Reactive Protein
- Cytokines
- DNA Primers
- Female
- Genotype
- Humans
- Inflammation
- Interleukin-6
- Interleukins
- Male