Article
Detection of factor V Leiden in Thai patients with venous thrombosis.
Asian Pacific journal of allergy and immunology - 1 Jun 2000
Prayoonwiwat W, Arnutti P, Hiyoshi M, Nathalang O, Suwanasophon C, Kokaseam R, Krutvecho T, Tatsumi N
Abstract excerpt
The molecular defect underlying activated protein C resistance (APC-R) is caused by a G to A point mutation in the codon for arginine 506 in the factor V gene (factor V Leiden) which is a major risk factor for venous thrombosis, especially in Caucasian populations. This study is an analysis of the Thai population to determine the prevalence of the factor V Leiden mutation. Twenty-seven patients with apparent...
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