Article
Factor V Leiden (FVQ 506) is common in a Brazilian population.
American journal of hematology - 1 Jul 1995
Arruda V R, Annichino-Bizzacchi J M, Costa F F, Reitsma P H
Abstract excerpt
Resistance to activated protein C (APC) is the most common risk factor in venous thrombosis. A missense mutation in the factor V gene (factor V Leiden) is the molecular basis for this phenotype. Factor V Leiden was previously found in about 20% of unselected patients with thrombosis but also occu...
Topics
- Base Sequence
- Brazil
- DNA
- Drug Resistance
- Enzyme Activation
- Factor V
- Gene Frequency
- Humans
- Molecular Sequence Data
- Mutation
- Netherlands
- Protein C
- Thrombophlebitis