Article
Factor V Leiden mutation in one family of Chinese origin.
Chinese medical journal - 1 Apr 2001
Wu J, Gu J, Xu J, Wang J, Sun Z, Smirnov M D, Morrissey J H, Esmon N
Abstract excerpt
OBJECTIVE: To investigate the factor V Leiden mutation associated with activated protein C resistance (APCR) in Chinese. METHODS: Thirty "normal" individuals and twenty patients with thrombotic disease from Chinese Han Nationality were studied with APTT +/- APC, PCR followed by MnLI restriction enzyme analysis, PCR based direct sequence-specific primers (PCR-SSP) and DNA sequence analysis. RESULTS: In one healthy...
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