Article
The first report of CCR5 delta 32 mutant in Thai injecting drug users.
Asian Pacific journal of allergy and immunology - 1 Jun 2000
Ruchusatsawat N, Vongsheree S, Thaisri H, Phutiprawan T
Abstract excerpt
CCR5, a chemokine receptor, is the principal coreceptor for macrophage-tropic HIV-1 which is the most important variant for viral transmission. It has been demonstrated that a homozygous genotype of a 32-bp deletion in CCR5 gene (delta32CCR5) shows a high degree of resistance to HIV-1 infection. To demonstrate that delta32CCR5 does exist in Thai natives, the CCR5 genotypes and allelic frequencies in 860 Thai...
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