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Article

Different oncological features of colorectal cancer codon-specific KRAS mutations: Not codon 13 but codon 12 have prognostic value.

World journal of gastroenterology - 28 Aug 2023

Ahn Hong-Min, Kim Duck-Woo, Oh Hyeon Jeong, Kim Hyung Kyung, Lee Hye Seung, Lee Tae Gyun, Shin Hye-Rim, Yang In Jun, Lee Jeehye, Suh Jung Wook, Oh Heung-Kwon, Kang Sung-Bum

Abstract excerpt

BACKGROUND: Approximately 40% of colorectal cancer (CRC) cases are linked to Kirsten rat sarcoma viral oncogene homolog (KRAS) mutations. KRAS mutations are associated with poor CRC prognosis, especially KRAS codon 12 mutation, which is associated with metastasis and poorer survival. However, the clinicopathological characteristics and prognosis of KRAS codon 13 mutation in CRC remain unclear. AIM: To evaluate...

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PMID: 37701134
DOI: 10.3748/wjg.v29.i32.4883
PMCID: PMC10494767

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Different oncological features of colorectal cancer codon-specific KRAS mutations: Not codon 13 but codon 12 have prognostic value.PMID 37701134Read ↗

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