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Article

Characterization of the chitin biosynthesis process as a compensatory mechanism in the fks1 mutant of Saccharomyces cerevisiae.

FEBS letters - 28 Jul 2000

García-Rodriguez L J, Trilla J A, Castro C, Valdivieso M H, Durán A, Roncero C

Abstract excerpt

Deletion of the 1,3-beta-D-glucan synthase gene FKS1 in Saccharomyces cerevisiae induces a compensatory mechanism that is reflected in a significant increase in chitin synthase III (CSIII) activity, leading to high rates of chitin synthesis. Deregulation of CSIII activity is mainly due to the intracellular delocalization of Chs3p and Chs4p, the two main components of the CSIII active complex.

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Identifiers

PMID: 10922474
DOI: 10.1016/s0014-5793(00)01835-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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