Article
Molecular and genetic control of chitin biosynthesis in fungi.
Archives of medical research - 1 Jan 1995
Ruiz-Herrera J, Xoconostle-Cazares B
Abstract excerpt
Chitin is the most important structural component of the cell walls of fungi. Its synthesis involves the transfer of N-acetylglucosaminyl residues from the universal donor UDPGlcNAC to the growing chain. This reaction is catalyzed by an ill-defined enzyme called chitin synthetase. By use of diverse techniques, including reverse genetics, it has been possible to isolate mutants affected in chitin biosynthesis in...
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