Article
P53 polymorphism in codon 72 and risk of human papillomavirus-induced cervical cancer: effect of inter-laboratory variation.
International journal of cancer - 15 Aug 2000
Makni H, Franco E L, Kaiano J, Villa L L, Labrecque S, Dudley R, Storey A, Matlashewski G
Abstract excerpt
An association between codon-72 p53 polymorphism and risk of human papillomavirus (HPV)-induced cervical cancer has been found recently, but it has been difficult to replicate. In this study, we assess the impact of inter-laboratory variation in p53 genotyping on the validity of the proposed association. DNA specimens were randomly selected from 54 invasive, squamous cell carcinoma cases, 52 HPV-negative, and 39...
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