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TP53 codon 72 polymorphism and risk for cervical cancer in Portugal.

Cancer genetics and cytogenetics - 1 Jun 2005

Santos Alexandra M, Sousa Hugo, Catarino Raquel, Pinto Daniela, Pereira Deolinda, Vasconcelos André, Matos Ana, Lopes Carlos, Medeiros Rui

Abstract excerpt

High-risk human papillomavirus are essential for the development of cervical cancer; however, TP53 is the most frequently altered tumor suppressor gene among tumors and is described as a cofactor for cervical carcinogenesis. TP53 has two common polymorphic forms encoding either proline or arginine, at position 72, and the presence of homozygous arginine has been reported as a risk factor for cervical cancer in...

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Identifiers

PMID: 15899386
DOI: 10.1016/j.cancergencyto.2004.10.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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