Article
p53 codon 72 polymorphism and risk of intra-epithelial and invasive cervical neoplasia in Greek women.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Apr 2000
Agorastos T, Lambropoulos A F, Constantinidis T C, Kotsis A, Bontis J N
Abstract excerpt
In 1998, Storey and co-workers suggested that individuals homozygous for arginine (Arg) at codon 72 of the p53 gene are about seven times more susceptible to human papillomavirus (HPV)-related carcinogenesis than heterozygotes. Since then, several studies from Northern Europe, Japan and the USA have failed to demonstrate a similar correlation. By contrast, a study in Brazil as well as one recent study in Italian...
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