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Article

Functional constraints of nuclear-mitochondrial DNA interactions in xenomitochondrial rodent cell lines.

The Journal of biological chemistry - 6 Oct 2000

Dey R, Barrientos A, Moraes C T

Abstract excerpt

The co-evolution of nuclear and mitochondrial genomes in vertebrates led to more than 100 specific interactions that are crucial for an optimized ATP generation. These interactions have been examined by introducing rat mtDNA into mouse cells devoid of mitochondrial DNA (mtDNA). When mtDNA-less ce...

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PMID: 10908562
DOI: 10.1074/jbc.M004053200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-10908562-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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