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Article

Genetic and functional analysis of mitochondrial DNA-encoded complex I genes.

Annals of the New York Academy of Sciences - 1 Apr 2004

Bai Yidong, Hu Peiqing, Park Jeong Soon, Deng Jian-Hong, Song Xiufeng, Chomyn Anne, Yagi Takao, Attardi Giuseppe

Abstract excerpt

Mammalian mitochondrial NADH dehydrogenase (complex I) is a multimeric complex consisting of at least 45 subunits, 7 of which are encoded by mitochondrial DNA (mtDNA). The function of these subunits is largely unknown. We have established an efficient method to isolate and characterize cells carrying mutations in various mtDNA-encoded complex I genes. With this method, 15 mouse cell lines with deficiencies in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15126303
DOI: 10.1007/978-3-662-41088-2_26

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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