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Article

Photoaging-associated large-scale deletions of mitochondrial DNA.

Methods in enzymology - 1 Jan 2000

Berneburg M, Krutmann J

Abstract excerpt

Heteroplasmy, replicative segregation, low copy numbers of mtDNA, and selection mechanisms at the molecular and cellular level are all factors that determine requirements toward the experimental design for the detection and the quantification of mtDNA mutations. The short half-life and low stability of ROS further increase the technical demands. However, the continuous improvement of techniques has given us more...

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Identifiers

PMID: 10907527
DOI: 10.1016/s0076-6879(00)19036-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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