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Article

Association between the interleukin 4 gene -590C>T promoter polymorphism and asthma in Xinjiang Uighur children.

Genetics and molecular research : GMR - 25 Jul 2016

Zhang J H, Zhou G H, Wei T T, Chang Z S

Abstract excerpt

We investigated the association between the interleukin 4 gene (IL-4) -590C>T polymorphism and forced expiratory volume in one second (FEV1) values, immunoglobulin E (IgE) levels, and susceptibility to asthma in Uighur children. IL-4 -590C>T frequencies were analyzed in 38 bronchial asthmatic patients and 35 non-asthmatic controls. Polymerase chain reaction and direct sequencing were applied to determine the...

Topics

Adolescent
Alleles
Asian People
Asthma
Child
Child, Preschool
China
Female
Gene Frequency
Genetic Predisposition to Disease
Humans
Interleukin-4

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 27525870
DOI: 10.4238/gmr.15038363

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-27525870-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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