Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fluoroquinolone resistance associated with target mutations and active efflux in oropharyngeal colonizing isolates of viridans group streptococci.

Antimicrobial agents and chemotherapy - 1 Aug 2000

Guerin F, Varon E, Hoï A B, Gutmann L, Podglajen I

Abstract excerpt

Oropharyngeal samples from 60 hospitalized patients (30 fluoroquinolone [FQ]-treated and 30 non-FQ-treated patients) and 30 untreated nonhospitalized healthy control subjects yielded 20 isolates of viridans group streptococci with reduced susceptibility to FQ, mostly from the hospitalized patient...

Topics

Anti-Infective Agents
Biological Transport, Active
DNA Topoisomerases, Type I
Drug Resistance, Microbial
Fluoroquinolones
Humans
Microbial Sensitivity Tests
Molecular Sequence Data
Mutation
Oropharynx
Streptococcus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Transformation, Bacterial

Source

Open in PubMed Open full text

Identifiers

PMID: 10898702
DOI: 10.1128/AAC.44.8.2197-2200.2000
PMCID: PMC90040

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-10898702-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Fluoroquinolone resistance associated with target mutations and active efflux in oropharyngeal colonizing isolates of viridans group streptococci.PMID 10898702Read ↗

Fluoroquinolone resistance in atypical pneumococci and oral streptococci: evidence of horizontal gene transfer of fluoroquinolone resistance determinants from Streptococcus pneumoniae.Semantic proximity Read ↗

Role of active efflux in association with target gene mutations in fluoroquinolone resistance in clinical isolates of Vibrio cholerae.Semantic proximity Read ↗

Drug efflux and parC mutations are involved in fluoroquinolone resistance in viridans group streptococci.Semantic proximity Read ↗

Target site modifications and efflux phenotype in clinical isolates of Streptococcus pneumoniae from Hong Kong with reduced susceptibility to fluoroquinolones.Semantic proximity Read ↗

Clinically relevant chromosomally encoded multidrug resistance efflux pumps in bacteria.Semantic proximity Read ↗

Mechanisms of resistance to quinolones: target alterations, decreased accumulation and DNA gyrase protectionSemantic proximity Read ↗

Molecular characterization and phylogenetic analysis of quinolone resistance-determining regions (QRDRs) of gyrA, gyrB, parC and parE gene loci in viridans group streptococci isolated from adult patients with cystic fibrosisSemantic proximity Read ↗

Clinical implications of multiple drug resistance efflux pumps of pathogenic bacteriaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.