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Article

Drug efflux and parC mutations are involved in fluoroquinolone resistance in viridans group streptococci.

Antimicrobial agents and chemotherapy - 1 Oct 1999

Ferrándiz M J, Oteo J, Aracil B, Gómez-Garcés J L, De La Campa A G

Abstract excerpt

Nine ciprofloxacin-resistant viridans group streptococci isolated from asymptomatic carriers were analyzed. Identification to the species level by using three different commercial systems and a PCR-based approach was inconsistent. The nucleotide sequences of fragments of the parC, parE, gyrA, and gyrB genes showed considerable intra- and interspecies variations, and these variations mainly involved silent...

Topics

Anti-Infective Agents
Bacterial Proteins
Biological Transport
DNA Gyrase
DNA Topoisomerase IV
DNA Topoisomerases, Type II
DNA-Binding Proteins
Drug Resistance, Microbial
Fluoroquinolones
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Microbial Sensitivity Tests

Molecular Sequence Data

Mutation

Phenotype

Streptococcus

Source

Open in PubMed Open full text

Identifiers

PMID: 10508036
DOI: 10.1128/AAC.43.10.2520
PMCID: PMC89512

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-10508036-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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