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Article

Role of active efflux in association with target gene mutations in fluoroquinolone resistance in clinical isolates of Vibrio cholerae.

Antimicrobial agents and chemotherapy - 1 Aug 2002

Baranwal Somesh, Dey Keya, Ramamurthy T, Nair G Balakrish, Kundu Manikuntala

Abstract excerpt

Quinolones are among the drugs of choice in the management of cholera caused by Vibrio cholerae. In this study, we demonstrate that, in addition to mutations detected in the target genes gyrA and parC, proton motive force-dependent efflux is involved in quinolone resistance in clinical isolates of V. cholerae.

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Source

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Identifiers

PMID: 12121955
DOI: 10.1128/AAC.46.8.2676-2678.2002
PMCID: PMC127385

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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