Article
PPP1R13L variant associated with prognosis for patients with rectal cancer.
Journal of cancer research and clinical oncology - 1 Mar 2013
Chae Yee Soo, Kim Jong Gwang, Kang Byung Woog, Lee Soo Jung, Jeon Hyo-Sung, Park Jun Seok, Choi Gyu Seog, Lee Won Kee
Abstract excerpt
BACKGROUND: ERCC1, CD3EAP, and PPP1R13L polymorphisms in the chromosomal region 19q13.2-3 have already been shown to have a synergistic effect on apoptosis and DNA repair pathways. Therefore, the aim of this study was to investigate the association between such genetic variants and the prognosis of colorectal cancer (CRC) following curative surgery. METHODS: DNA was extracted from fresh frozen normal tissue from...
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