Article
Mutational analysis of the putative receptor-binding domain of Moloney murine leukemia virus glycoprotein gp70.
Virology - 20 Jul 2000
Panda B R, Kingsman S M, Kingsman A J
Abstract excerpt
The entry of Moloney murine leukemia virus (MoMuLV) to murine cells is mediated by the binding of its envelope glycoprotein gp70 to its receptor, the cationic amino acid transporter MCAT-1. The binding property of the envelope protein lies mainly in the N-terminal half of the protein. To identify essential residues involved in the binding of gp70 to its receptor, we have mutated amino acids within the putative...
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