Article
Modulation of ecotropic murine retroviruses by N-linked glycosylation of the cell surface receptor/amino acid transporter.
Journal of virology - 1 Oct 1996
Wang H, Klamo E, Kuhmann S E, Kozak S L, Kavanaugh M P, Kabat D
Abstract excerpt
The cell surface receptor for ecotropic host-range (infection limited to mice or rats) murine leukemia viruses (MuLVs) is the widely expressed system y+ transporter for cationic amino acids (CAT-1). Like other retroviruses, ecotropic MuLV infection eliminates virus-binding sites from cell surface...
Topics
- Amino Acid Sequence
- Amino Acid Transport Systems
- Animals
- Carrier Proteins
- Cell Line
- Cricetinae
- Down-Regulation
- Glycosylation
- Humans
- Leukemia Virus, Murine
- Mice
- Molecular Sequence Data
