Article
Predominant appearance of NK1.1+ T cells producing IL-4 may be involved in the increased susceptibility of mice with the beige mutation during Salmonella infection.
Journal of immunology (Baltimore, Md. : 1950) - 1 Mar 1997
Enomoto A, Nishimura H, Yoshikai Y
Abstract excerpt
C57BL/6 mice with the beige mutation (beige mice) showed a high susceptibility to infection with Salmonella choleraesuis compared with C57BL/6 (B6) control mice, as assessed by bacterial number in the peritoneal cavity and the liver. The appearance of NK1.1+ CD3- NK cells was significantly suppre...
Topics
- Animals
- Antibodies, Monoclonal
- Antigens
- Antigens, Ly
- Antigens, Surface
- CD3 Complex
- Disease Susceptibility
- Female
- Immunophenotyping
- Injections, Intraperitoneal
- Interleukin-12
- Interleukin-4
- Killer Cells, Natural
- Lectins, C-Type
- Lymphocyte Activation
- Mice
- Mice, Inbred C57BL
- Mutation