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Article

Heritability of elevated factor VIII antigen levels in factor V Leiden families with thrombophilia.

British journal of haematology - 1 Jun 2000

Kamphuisen P W, Lensen R, Houwing-Duistermaat J J, Eikenboom J C, Harvey M, Bertina R M, Rosendaal F R

Abstract excerpt

Factor VIII activity (factor VIII:C) and factor VIII antigen (factor VIII:Ag) levels above 150 IU/dl are associated with a five- to sixfold increased risk of venous thrombosis compared with levels < 100 IU/dl. These high levels are present in 25% of patients with a first episode of deep-vein thrombosis and in 11% of healthy controls. von Willebrand factor (VWF) and blood group are important determinants of the...

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Source

Identifiers

PMID: 10886197
DOI: 10.1046/j.1365-2141.2000.02091.x

Genes

VWF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Heritability of elevated factor VIII antigen levels in factor V Leiden families with thrombophilia.PMID 10886197Read ↗

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