Article
Familial clustering of high factor VIII levels in patients with venous thromboembolism.
Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2001
Schambeck C M, Hinney K, Haubitz I, Mansouri Taleghani B, Wahler D, Keller F
Abstract excerpt
High levels of factor VIII (FVIII) but not von Willebrand factor (vWF) are known to increase the risk for venous thromboembolism. Whether high FVIII levels originate from hereditary defects or from acquired conditions remains unanswered. The objective of our study was to investigate whether there is evidence for familial clustering of elevated FVIII levels in families in which >/=1 member has been affected by a...
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