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Article

Development. PARallels in axis formation.

Science (New York, N.Y.) - 9 Jun 2000

Morris J, Lehmann R, Navarro C

Abstract excerpt

There is an intricate network of molecules called cell fate determinants that instruct the cells of the embryo to take on either an anterior or posterior fate. In a lively Perspective, Lehmann and her colleagues discuss new findings in the fruit fly that identify a key protein, PAR-1, which ensures that the cell fate determinants are themselves located in the correct region of the oocyte. In this way, the...

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Identifiers

PMID: 10877696
DOI: 10.1126/science.288.5472.1759

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Development. PARallels in axis formation.PMID 10877696Read ↗

A Drosophila melanogaster homologue of Caenorhabditis elegans par-1 acts at an early step in embryonic-axis formation.Semantic proximity Read ↗

Investigating the underlying mechanisms of axis formation in Drosophila melanogasterSemantic proximity Read ↗

Bazooka is required for polarisation of the Drosophila anterior-posterior axis.Semantic proximity Read ↗

Symmetry breaking during Drosophila oogenesis.Semantic proximity Read ↗

Follicle cell contact maintains main body axis polarity in the <i>Drosophila melanogaster</i> oocyteSemantic proximity Read ↗

The PAR proteins: fundamental players in animal cell polarization.Semantic proximity Read ↗

The Drosophila AP axis is polarised by the cadherin-mediated positioning of the oocyte.Semantic proximity Read ↗

The origin of asymmetry: early polarisation of the Drosophila germline cyst and oocyte.Semantic proximity Read ↗

Drosophila par-1 is required for oocyte differentiation and microtubule organization.Semantic proximity Read ↗

Anterior PAR proteins function during cytokinesis and maintain DYN-1 at the cleavage furrow in Caenorhabditis elegans.Semantic proximity Read ↗

Bazooka and atypical protein kinase C are required to regulate oocyte differentiation in the <i>Drosophila</i> ovarySemantic proximity Read ↗

Polarization of both major body axes in Drosophila by gurken-torpedo signalling.Semantic proximity Read ↗

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