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Article

Genotype effects on neurodegeneration and neuroadaptation in monoaminergic neurotransmitter systems.

Neurochemistry international - 1 Jan 2000

Heinz A, Goldman D

Abstract excerpt

Neuroadaptation and neurodegeneration in central dopaminergic and serotonergic systems are central to vulnerability, process and consequences of addictive behavior. Serotonergic dysfunction has been associated with behavior disinhibition and negative mood states that may predispose to excessive alcohol intake, while alcohol-induced stimulation of dopaminergic neurotransmission may encode the reinforcing...

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PMID: 10871694
DOI: 10.1016/s0197-0186(00)00057-7

Genes

HTT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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