Article
Pharmacogenetic insights to monoaminergic dysfunction in alcohol dependence.
Psychopharmacology - 1 Aug 2004
Heinz Andreas, Goldman David, Gallinat Jürgen, Schumann Gunter, Puls Imke
Abstract excerpt
RATIONALE: Alcohol dependence is characterized by the development of tolerance, withdrawal symptoms, and craving for alcohol. Chronic alcohol consumption causes neuroadaptive changes in the central dopaminergic and serotonergic system, which are partially reversible after detoxification. The seve...
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