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Article

Polymorphisms in the dopamine transporter gene (SLC6A3/DAT1) and alcohol dependence in humans: a systematic review.

Pharmacogenomics - 1 May 2009

van der Zwaluw Carmen S, Engels Rutger C M E, Buitelaar Jan, Verkes Robbert J, Franke Barbara, Scholte Ron H J

Abstract excerpt

Dopamine neurotransmission has been a key player in attempts to identify genetic factors involved in alcohol dependence. The dopamine transporter terminates dopaminergic neurotransmission, making the gene encoding the transporter (SLC6A3/DAT1) an attractive candidate in clinical studies on alcohol dependence. We conducted a systematic review of 18 studies examining associations between polymorphisms in DAT1 and...

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Identifiers

PMID: 19450132
DOI: 10.2217/pgs.09.24

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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