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Article

Genetic characterization of Escherichia coli type 1 pilus adhesin mutants and identification of a novel binding phenotype.

Journal of bacteriology - 1 Jul 2000

Hamrick T S, Harris S L, Spears P A, Havell E A, Horton J R, Russell P W, Orndorff P E

Abstract excerpt

Five Escherichia coli type 1 pilus mutants that had point mutations in fimH, the gene encoding the type 1 pilus adhesin FimH, were characterized. FimH is a minor component of type 1 pili that is required for the pili to bind and agglutinate guinea pig erythrocytes in a mannose-inhibitable manner. Point mutations were located by DNA sequencing and deletion mapping. All mutations mapped within the signal sequence...

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Source

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Identifiers

PMID: 10869080
DOI: 10.1128/JB.182.14.4012-4021.2000
PMCID: PMC94587

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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