Article
Evolutionary analysis points to divergent physiological roles of type 1 fimbriae in Salmonella and Escherichia coli.
mBio - 5 Mar 2013
Kisiela Dagmara I, Chattopadhyay Sujay, Tchesnokova Veronika, Paul Sandip, Weissman Scott J, Medenica Irena, Clegg Steven, Sokurenko Evgeni V
Abstract excerpt
UNLABELLED: Salmonella and Escherichia coli mannose-binding type 1 fimbriae exhibit highly similar receptor specificities, morphologies, and mechanisms of assembly but are nonorthologous in nature, i.e., not closely related evolutionarily. Their operons differ in chromosomal location, gene arrangement, and regulatory components. In the current study, we performed a comparative genetic and structural analysis of...
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