Article
Clonal response of K562 leukemic cells to exogenous p21WAF1.
Leukemia research - 1 Jul 2000
Steinman R A, Yaroslavskiy B, Kaplan S S, Goff J P, Shields D S
Abstract excerpt
The p21WAF1 protein is involved in the control of cell differentiation and proliferation. We have previously shown that p21WAF1 is upregulated in normal, proliferating hematopoietic cells undergoing differentiation. Exogenous p21WAF1 has been reported to increase colony-formation by normal hematopoietic progenitors. We examined the effects of exogenous p21WAF1 on proliferation, differentiation, gene expression...
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