Article
Induced p21WAF1 expression acts to reverse myc myelomonocytic cell transformation.
Cancer gene therapy - 1 Nov 2000
Dolnikov A, Millington M, Sun L Q, Symonds G
Abstract excerpt
Two murine myelomonocytic cells lines were used to examine p21WAF1 expression in myc-induced cell transformation. tEMmyc4 and FDLV are two v-myc-transformed immortalised myeloid cell lines exhibiting different transformed phenotypes. FDLV cells were derived from the transduction of v-myc into FDC-P1 cells and retain growth factor (IL-3) dependence, whereas tEMmyc4 cells were derived from the transduction of...
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