Article
Mutational analysis of the cytoplasmic tail of the human transferrin receptor. Identification of a sub-domain that is required for rapid endocytosis.
The Journal of biological chemistry - 5 Oct 1991
Gironès N, Alverez E, Seth A, Lin I M, Latour D A, Davis R J
Abstract excerpt
It has been reported that the sequence Tyr20-X-Arg-Phe23 present within the cytoplasmic tail of the transferrin receptor may represent a tyrosine internalization signal (Collawn, J.F., Stangel, M., Kuhn, L.A., Esekogwu, V., Jing, S., Trowbridge, I.S., and Tainer, J. A. (1990) Cell 63, 1061-1072)....
Topics
- Amino Acid Sequence
- Animals
- Cell Line
- Cricetinae
- Cytoplasm
- Endocytosis
- Humans
- Kinetics
- Molecular Sequence Data
- Mutation
- Receptors, LDL
- Receptors, Transferrin
- Tyrosine