Article
A new family of nuclear receptor coregulators that integrate nuclear receptor signaling through CREB-binding protein.
Molecular and cellular biology - 1 Jul 2000
Mahajan M A, Samuels H H
Abstract excerpt
We describe the cloning and characterization of a new family of nuclear receptor coregulators (NRCs) which modulate the function of nuclear hormone receptors in a ligand-dependent manner. NRCs are expressed as alternatively spliced isoforms which may exhibit different intrinsic activities and receptor specificities. The NRCs are organized into several modular structures and contain a single functional LXXLL motif...
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