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Article

Expression and role of nuclear receptor coregulators in colorectal cancer

1 Jan 2017

Abstract excerpt

Colorectal cancer (CRC) is one of the most common human cancers and the cause of about 700000 deaths per year worldwide. Deregulation of the WNT/β-catenin pathway is a key event in CRC initiation. This pathway interacts with other nuclear signaling pathways, including members of the nuclear receptor superfamily and their transcription coregulators. In this review, we provide an overview of the literature dealing...

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PMID: 28740336
DOI: 10.3748/wjg.v23.i25.4480

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