Article
Mosaic 13q14 deletions in peripheral leukocytes of non-hematologic cancer cases and healthy controls.
Journal of human genetics - 1 May 2016
Machiela Mitchell J, Zhou Weiyin, Caporaso Neil, Dean Michael, Gapstur Susan M, Goldin Lynn, Stevens Victoria L, Yeager Meredith, Chanock Stephen J
Abstract excerpt
Loss of 13q14.3 is a chromosomal event found in ~50% of B-cell chronic lymphocytic leukemia (CLL) and monoclonal B-cell lymphocytosis (MBL) cases. Surveys of somatic alterations in solid tumors have shown sporadic 13q14.3 loss in many different tumor types, but not at high frequency in any specific tumor type. In our recent survey of the single-nucleotide polymorphism (SNP) microarray data from 127 000...
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