Article
Vimentin intermediate filaments modulate the motility of mitochondria.
Molecular biology of the cell - 1 Jul 2011
Nekrasova Oxana E, Mendez Melissa G, Chernoivanenko Ivan S, Tyurin-Kuzmin Pyotr A, Kuczmarski Edward R, Gelfand Vladimir I, Goldman Robert D, Minin Alexander A
Abstract excerpt
Interactions with vimentin intermediate filaments (VimIFs) affect the motility, distribution, and anchorage of mitochondria. In cells lacking VimIFs or in which VimIF organization is disrupted, the motility of mitochondria is increased relative to control cells that express normal VimIF networks. Expression of wild-type VimIF in vimentin-null cells causes mitochondrial motility to return to normal (slower) rates....
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