Article
Interleukin 6 gene promoter polymorphism is not associated with ankylosing spondylitis.
The Journal of rheumatology - 1 Jun 2000
Collado-Escobar M D, Nieto A, Matarán L, Raya E, Martín J
Abstract excerpt
OBJECTIVE: To investigate the possible association between the recently described interleukin 6 (IL-6) promoter polymorphisms at position -174, and susceptibility to ankylosing spondylitis (AS). METHODS: Ninety-two patients with AS, 157 healthy controls, and an additional group of 52 HLA-B27 positive unrelated individuals were included in this study. The -174 polymorphic site in the promoter region of IL-6 gene...
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