Article
Lack of association between IL-6 gene polymorphisms and rheumatoid arthritis in Turkish population.
Rheumatology international - 1 Jul 2012
Arman A, Coker A, Sarioz O, Inanc N, Direskeneli H
Abstract excerpt
Inflammatory cytokines play an important role in the pathogenesis of rheumatoid arthritis (RA). One of candidate genes is interleukin-6 (IL-6), and single-nucleotide polymorphisms in the promoter region of IL-6 were found to be associated with RA. The aim of this study was to determine the association between IL-6 promoter polymorphisms (-174, -572, -597) and RA in Turkish population. A total of 425 subjects were...
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