The molecular and genetic basis of AD: The end of the beginning

Abstract excerpt

The Decade of the Brain—the 1990s—was a time of gains in our knowledge of the molecular and genetic basis of Alzheimer’s disease (AD).1-4 The momentum of discovery and depth of molecular information that developed during that time clearly leads one to predict that it is the end of the beginning of deciphering the pathogenesis of AD leading to effective therapy. Most cases of AD are sporadic; however, the...

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