Article
Ribosomal frameshifting in plants: a novel signal directs the -1 frameshift in the synthesis of the putative viral replicase of potato leafroll luteovirus.
The EMBO journal - 1 Mar 1992
Prüfer D, Tacke E, Schmitz J, Kull B, Kaufmann A, Rohde W
Abstract excerpt
The 5.8 kb RNA genome of potato leafroll luteovirus (PLRV) contains two overlapping open reading frames, ORF2a and ORF2b, which are characterized by helicase and RNA polymerase motifs, respectively, and possibly represent the viral replicase. Within the overlap, ORF2b lacks an AUG translational s...
Topics
- Amino Acid Sequence
- Base Sequence
- Electrophoresis, Polyacrylamide Gel
- Frameshift Mutation
- Gene Expression
- Glucuronidase
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Mutation
- Nucleic Acid Conformation
- Nucleic Acids
- Open Reading Frames
- Plant Viruses
- Protein Biosynthesis