Article
A sequence required for -1 ribosomal frameshifting located four kilobases downstream of the frameshift site.
Journal of molecular biology - 27 Jul 2001
Paul C P, Barry J K, Dinesh-Kumar S P, Brault V, Miller W A
Abstract excerpt
Programmed ribosomal frameshifting allows one mRNA to encode regulate expression of, multiple open reading frames (ORFs). The polymerase encoded by ORF 2 of Barley yellow dwarf virus (BYDV) is expressed via minus one (-1) frameshifting from the overlapping ORF 1. Previously, this appeared to be mediated by a 116 nt RNA sequence that contains canonical -1 frameshift signals including a shifty heptanucleotide...
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