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Programmed −1 ribosomal frameshifting in the SARS coronavirus

26 Oct 2004

Abstract excerpt

Programmed -1 ribosomal frameshifting is an alternate mechanism of translation used by coronavirus to synthesize replication proteins encoded by two overlapping open reading frames. For some coronaviruses, the mRNA cis-acting stimulatory structures involved in this process have been characterized, but their precise contribution to ribosomal frameshifting is not completely understood. Recently, a novel coronavirus...

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PMID: 15506971
DOI: 10.1042/bst0321081

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