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The 5'-proximal hairpin loop of lbi RNA is a key structural element in repression of D-galactan II biosynthesis in Klebsiella pneumoniae serotype O1.

Molecular microbiology - 1 May 2000

Warnecke J M, Nitschke M, Moolenaar C E, Rietschel E T, Hartmann R K, Mamat U

Abstract excerpt

The lbi (lipopolysaccharide biosynthesis interfering) RNA of phage Acm1, an untranslated RNA transcript of 97 nucleotides, previously shown to affect O-polysaccharide biosynthesis in various Escherichia coli strains, was found to downregulate the synthesis of the D-galactan II component of the O-specific polysaccharide in Klebsiella pneumoniae serotype O1. Enzymatic and Pb2+ probing experiments revealed that lbi...

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PMID: 10844658
DOI: 10.1046/j.1365-2958.2000.01894.x

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