Article
Aberrant expression of the major sialoglycoprotein (CD43) on the monocytes of patients with myelodysplastic syndromes.
Annals of hematology - 1 Apr 2000
Kyriakou D, Liapi D, Kyriakou E, Alexandrakis M, Vlachonikolis I G, Mavromanolakis M, Eliakis P, Eliopoulos G D
Abstract excerpt
CD43, a sialylated glycoprotein expressed on the surface of most hematopoietic cells, has been implicated in cell adhesion and signaling. The reduced expression of this antigen in patients with Wiscott-Aldrich syndrome, in which progressive immunodeficiency is a major problem, raised the question whether abnormal expression of this molecule could affect the susceptibility to infections in patients with...
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